Determination of Keto-deoxy-d-manno-8-octanoic acid (KDO) from Lipopolysaccharide of Escherichia coli
2-Keto-3-deoxy-octonate (KDO) is an essential constituent of lipopolysaccharide (LPS) that forms the outermost leaflet of Gram-negative bacterial outer membrane.LPS is mainly composed of lipid A, O-antigen wac 4011 and a core oligosaccharide.Two molecules of KDO are present per one molecule of LPS.A proper level of LPS is required to maintain the o